An attempt to determine a medium-term, low-dose asbestos exposure indicator on the basis of clinical and radiological lung changes
Awad, L; Lazar, P; Di Menza, L; Bignon, J; Bonnaud, G
HERO ID
2720949
Reference Type
Book/Book Chapter
Year
1980
Language
English
PMID
| HERO ID | 2720949 |
|---|---|
| Year | 1980 |
| Title | An attempt to determine a medium-term, low-dose asbestos exposure indicator on the basis of clinical and radiological lung changes |
| Book Title | Biological effects of mineral fibres |
| Authors | Awad, L; Lazar, P; Di Menza, L; Bignon, J; Bonnaud, G |
| Editor | Wagner, JC |
| Publisher Text | International Agency for Research on Cancer |
| City | Lyon, France |
| Page Numbers | 755-761 |
| Abstract | Clinical and radiological lung changes from asbestos (1332214) exposure were investigated in humans. Three groups of subjects who worked in buildings with insufficient protection against asbestos were examined clinically, functionally, and radiologically. Group 1, consisting of 160 subjects, worked directly in contact with asbestos sources; group 2, consisting of 277 subjects, worked at least 10 years in the building, but had no specific exposure; and group 3, consisting of 157 subjects, were comparisons who were exposed only during the construction period of the buildings. No differences in the three groups were observed on clinical examination of lymph nodes, rales, abnormal heart sounds, and tenderness of masses on palpation. Functional examinations showed group 1 was significantly higher than the other groups in cough, sputum, and breathlessness; groups 1 and 2 had significantly more chest pain. Radiologically, group 1 had significantly more diaphragmatic straightness, 12 percent as compared to 6 percent for groups 2 and 3. The average mean number of radiological abnormalities was significantly higher in group 1 than group 2 or 3. Possible confounding factors showed that smoking was more frequent in groups 1 and 3; previous tuberculosis and bronchitis were less frequent in group 1 and obesity was significantly higher in group 1. Possible past exposure was highest in group 1. |
| Pmid | 7228331 |
| Wosid | MEDLINE:7228331 |
| Is Certified Translation | No |
| Dupe Override | No |
| Series | IARC Scientific Publication no. 30 |
| Isbn | 9789283211303 |
| Comments | Source: https://publications.iarc.fr/Book-And-Report-Series/Iarc-Scientific-Publications/Biological-Effects-Of-Mineral-Fibres-Effets-Biologiques-Des-Fibres-Min%C3%A9rales-1980 |
| Is Public | Yes |
| Language Text | English |