Biotechnological significance of toxic marine dinoflagellates
Garcia Camacho, F; Gallardo Rodriguez, J; Sanchez Miron, A; Ceron Garcia, MC; Belarbi, EH; Chisti, Y; Molina Grima, E
| HERO ID | 2504867 |
|---|---|
| Material Type | Review |
| In Press | No |
| Year | 2007 |
| Title | Biotechnological significance of toxic marine dinoflagellates |
| Authors | Garcia Camacho, F; Gallardo Rodriguez, J; Sanchez Miron, A; Ceron Garcia, MC; Belarbi, EH; Chisti, Y; Molina Grima, E |
| Journal | Biotechnology Advances |
| Volume | 25 |
| Issue | 2 |
| Page Numbers | 176-194 |
| Abstract | Dinoflagellates are microalgae that are associated with the production of many marine toxins. These toxins poison fish, other wildlife and humans. Dinoflagellate-associated human poisonings include paralytic shellfish poisoning, diarrhetic shellfish poisoning, neurotoxic shellfish poisoning, and ciguatera fish poisoning. Dinotlagellate toxins and bioactives are of increasing interest because of their commercial impact, influence on safety of seafood, and potential medical and other applications. This review discusses biotechnological methods of identifying toxic dinoflagellates and detecting their toxins. Potential applications of the toxins are discussed. A lack of sufficient quantities of toxins for investigational purposes remains a significant limitation. Producing quantities of dinoflagellate bioactives requires an ability to mass culture them. Considerations relating to bioreactor culture of generally fragile and slow-growing dinoflagellates are discussed. Production and processing of dinoflagellates to extract bioactives, require attention to biosafety considerations as outlined in this review. (c) 2006 Elsevier Inc. All rights reserved. |
| Doi | 10.1016/j.biotechadv.2006.11.008 |
| Pmid | 17208406 |
| Wosid | WOS:000244412000004 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | algal toxins; ciguatera fish poisoning; diarrhetic shellfish poisoning; dinoflagellates; marine toxins; neurotoxic shellfish poisoning; paralytic shellfish poisoning |