Fine Particulate Matter And Risk Of Preterm Birth In Connecticut In 2000-2006: A Longitudinal Study

Pereira, G; Belanger, K; Ebisu, K; Bell, ML

HERO ID

2332545

Reference Type

Journal Article

Year

2014

Language

English

PMID

24068199

HERO ID 2332545
In Press No
Year 2014
Title Fine Particulate Matter And Risk Of Preterm Birth In Connecticut In 2000-2006: A Longitudinal Study
Authors Pereira, G; Belanger, K; Ebisu, K; Bell, ML
Journal American Journal of Epidemiology
Volume 179
Issue 1
Page Numbers 67-74
Abstract Several studies have examined associations between particulate matter with aerodynamic diameter of 2.5 µm or less (PM2.5) and preterm birth, but it is uncertain whether results were affected by individual predispositions (e.g., genetic factors, social conditions) that might vary considerably between women. We tested the hypothesis that a woman is at greater risk of preterm delivery when she has had elevated exposure to ambient PM2.5 during a pregnancy than when she has not by comparing pregnancies in the same woman. From 271,204 births, we selected 29,175 women who had vaginal singleton livebirths at least twice in Connecticut in 2000-2006 (n = 61,688 births). Analyses matched pregnancies to the same woman. Adjusted odds ratios per interquartile range (2.33-µg/m(3)) increase in PM2.5 in the first trimester, second trimester, third trimester, and whole pregnancy were 1.07 (95% confidence interval (CI): 1.00, 1.15), 0.96 (95% CI: 0.90, 1.03), 1.03 (95% CI: 0.97, 1.08), and 1.13 (95% CI: 1.01, 1.28), respectively. Among Hispanic women, the odds ratio per interquartile range increase in whole-pregnancy exposure was 1.31 (95% CI: 1.00, 1.73). Pregnancies with elevated PM2.5 exposure were more likely to result in preterm birth than were other pregnancies to the same woman at lower exposure. Associations were most pronounced in the first trimester and among Hispanic women.
Doi 10.1093/aje/kwt216
Pmid 24068199
Wosid WOS:000329061100010
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Keyword air pollution; environmental pollution; longitudinal studies; particulate matter; pregnancy; pregnancy outcomes; preterm birth