Invited commentary: epidemiologic studies of the impact of air pollution on lung cancer

Hart, JE

HERO ID

2232187

Reference Type

Journal Article

Subtype

Comment

Year

2014

Language

English

PMID

24287471

HERO ID 2232187
Material Type Comment
In Press No
Year 2014
Title Invited commentary: epidemiologic studies of the impact of air pollution on lung cancer
Authors Hart, JE
Journal American Journal of Epidemiology
Volume 179
Issue 4
Page Numbers 452-454
Abstract In this issue of the Journal, Villeneuve et al. (Am J Epidemiol. 2014;179(4):443-451) present epidemiologic evidence supporting the literature on the adverse effects of air pollution on risk of lung cancer. They found that ambient exposure to volatile organic compounds, especially when measured at longer time scales, was associated with increased odds of lung cancer in citizens of Toronto, Ontario, Canada, between 1997 and 2002. Specifically, in fully adjusted models, they observed that an interquartile-range increase in benzene concentration was associated with an odds ratio of 1.51 (95% confidence interval: 1.13, 2.01) using exposure at the time of interview. The odds ratio increased to 1.84 (95% confidence interval: 1.26, 2.68) when time-weighted exposure at all previous addresses was considered. They obtained similar results for exposure to nitrogen dioxide. These findings add weight to the substantial (and rapidly growing) body of literature on the relation of air pollution with lung cancer risk, as well as illustrate important aspects of the effects of different exposure assessment choices and potential sources of key interest.
Doi 10.1093/aje/kwt290
Pmid 24287471
Wosid WOS:000331264100006
Url https://www.proquest.com/docview/1505339629?accountid=171501&bdid=64565&_bd=4RnQZQ5kPaV8WuJFobLfVUgy2h4%3D
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Keyword air pollution; lung cancer; nitrogen dioxide; volatile organic compounds