The effects of 2-acetylaminofluorene and nitrite on free radicals and carcinogenesis in rat liver

Commoner, B; Woolum, JC; Senturia, BH; Ternberg, JL

HERO ID

2221959

Reference Type

Journal Article

Year

1970

Language

English

PMID

4318918

HERO ID 2221959
In Press No
Year 1970
Title The effects of 2-acetylaminofluorene and nitrite on free radicals and carcinogenesis in rat liver
Authors Commoner, B; Woolum, JC; Senturia, BH; Ternberg, JL
Journal Cancer Research
Volume 30
Issue 8
Page Numbers 2091-2097
Abstract The intensity of the abnormal electron spin resonance signal previously observed in the livers of rats which were fed various chemical carcinogens is found to depend on the intake of the carcinogen, protein, and nitrate or nitrite. Nitrite enhances the intensity of the abnormal electron spin resonance signal and inhibits the carcinogenicity of 2-acetyl-aminofluorene. The appearance of the signal-bearing complex and the possible mechanism of its anticarcinogenic activity are discussed.
Pmid 4318918
Wosid WOS:A1970H311300004
Url https://aacrjournals.org/cancerres/article/30/8/2091/478187/The-Effects-of-2-Acetylaminofluorene-and-Nitrite
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English