Elevated concentrations of alpha-tocopherol, ascorbic acid, and serum lipid in rats fed polychlorinated biphenyls, chlorobutanol, or phenobarbital
Katayama, T; Momota, Y; Watanabe, Y; Kato, N
HERO ID
2200724
Reference Type
Journal Article
Year
1991
Language
English
| HERO ID | 2200724 |
|---|---|
| In Press | No |
| Year | 1991 |
| Title | Elevated concentrations of alpha-tocopherol, ascorbic acid, and serum lipid in rats fed polychlorinated biphenyls, chlorobutanol, or phenobarbital |
| Authors | Katayama, T; Momota, Y; Watanabe, Y; Kato, N |
| Journal | Journal of Nutritional Biochemistry |
| Volume | 2 |
| Issue | 2 |
| Page Numbers | 92-96 |
| Abstract | BIOSIS COPYRIGHT: BIOL ABS. Experiments were conducted with growing rats to investigate the effects of dietary 0.05% polychlorinated biphenyls (PCB), 0.3% chlorobutanol (Chloretone), and 0.2% phenobarbital sodium on intestinal absorption of alpha-tocopherol and serum and tissue lipids, and the influence of dietary 5% pectin and 0.2% ethyl p-chlorophenoxyisobutyrate (clofibrate) on the changes in these lipids due to dietary 0.4% Chloretone. Dietary addition of PCB increased serum concentrations of alpha-tocopherol, cholesterol, and phospholipids. These were mainly attributed to the increments in the fraction of high-density lipoproteins. PCB intake increased tissue alpha-tocopherol and apparent absorption of alpha-tocopherol from intestine. Similar changes in serum and tissue lipids and in intestinal absorption of alpha-tocopherol were observed with dietary Chloretone and phenobarbital. Dietary clofibrate and pectin depressed the increase in serum concentrations of these lipids by Chloretone. Change |
| Wosid | WOS:A1991EV48700005 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | ALPHA-TOCOPHEROL; CHOLESTEROL; XENOBIOTICS; CLOFIBRATE; PECTIN; INTESTINAL ABSORPTION OF ALPHA-TOCOPHEROL |
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