Reproductive characteristics and corticoid levels of female white-footed mice fed ad libitum and restricted diets containing a polychlorinated biphenyl

Sanders, OT; Kirkpatrick, RL

HERO ID

2179086

Reference Type

Journal Article

Year

1977

Language

English

PMID

407075

HERO ID 2179086
In Press No
Year 1977
Title Reproductive characteristics and corticoid levels of female white-footed mice fed ad libitum and restricted diets containing a polychlorinated biphenyl
Authors Sanders, OT; Kirkpatrick, RL
Journal Environmental Research
Volume 13
Issue 3
Page Numbers 358-363
Abstract HEEP COPYRIGHT: BIOL ABS. Sixty female white-footed mice (Peromyscus leucopus) were fed either ad lib or 70% ad lib diets for 5 wk. During the last 3 wk of feeding a polychlorinated biphenyl (Aroclor 1254) was incorporated into the diets at levels of 0, 25 or 100 ppm (based on ad lib intake). Polychlorinated biphenyl ingestion increased liver weights, reduced pentobarbital-induced sleep times, and generally reduced plasma corticoid levels but had no effect on reproductive organ weights or the incidence of estrus (as judged by vaginal smears). Feed restriction caused marked atrophy of the ovaries and uterus and reduced the incidence of estrus.
Doi 10.1016/0013-9351(77)90015-9
Pmid 407075
Wosid WOS:A1977DJ17100002
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
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