Biochemical response in rats exposed to delor 105

Kosinova, A; Ginter, E; Gornerova, E; Mlynarcikova, U; Madaric, A

HERO ID

2170997

Reference Type

Journal Article

Year

1985

Language

English

HERO ID 2170997
In Press No
Year 1985
Title Biochemical response in rats exposed to delor 105
Authors Kosinova, A; Ginter, E; Gornerova, E; Mlynarcikova, U; Madaric, A
Journal Biologia
Volume 40
Issue 8
Page Numbers 785-790
Abstract Rats were treated four days with an oral dose of 25 mg/kg/day of Delor 105 (polychlorinated biphenyls produced in Czechoslovakia). Significant increase in the relative liver weight, hepatal vitamin C, amount of proteins, p-nitroanisole 0-demethylase, aniline hydroxylase and cytochrome P-450 in isolated liver microsomes was observed. The levels of total blood cholesterol as well as HDL cholesterol were significantly elevated on the fourth day of the treatment. Close direct linear correlation between hepatal vitamin C and microsomal cytochrome P-450 was found.
Wosid WOS:A1985ARR7300006
Url <Go to ISI>://WOS:A1985ARR7300006
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English