Parenteral nutrition for premature infant and aluminum intakes
Micard, S; Durand, JL; Daoud, P; Maison, C
| HERO ID | 2066780 |
|---|---|
| In Press | No |
| Year | 1998 |
| Title | Parenteral nutrition for premature infant and aluminum intakes |
| Authors | Micard, S; Durand, JL; Daoud, P; Maison, C |
| Journal | Journal de Pharmacie Clinique |
| Volume | 17 |
| Issue | 4 |
| Page Numbers | 249-252 |
| Abstract | BIOSIS COPYRIGHT: BIOL ABS. Aluminum (Al), one of the most widespread element on earth, often contaminates preparations such as parenteral nutrition solutions. Small-volume additives such as calcium gluconate and phosphate salts solutions are the most contaminated. Large-volume parental source solutions such as dextrose, crystalline amino acids and lipid emulsions are significantly less contaminated. Premature infants generally need intravenous feeding and are therefore vulnerable to aluminum toxicity: protective gastrointestinal mechanisms are bypassed and renal function is immature. Several studies showed that Al blood levels and urinary excretion increase when premature infants received parenteral nutrition. Urinary elimination is not adequate and Al accumulation is observed in tissues, especially in bones. Recently, in preterm infants, prolonged intravenous feeding with solutions containing Al was demonstrated to be associated with impaired neurologic development. Montreuil Hospital intensive c |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | fre |