Multiple path particle dosimetry model (MPPD v 1.0): A model for human and rat airway particle dosimetry
Price, OT; Asgharian, B; Miller, FJ; Cassee, FR; de Winter-Sorkina, R
HERO ID
202677
Reference Type
Data & Software
Subtype
Computer Program
Year
2002
Language
English
| HERO ID | 202677 |
|---|---|
| Material Type | Computer Program |
| Year | 2002 |
| Title | Multiple path particle dosimetry model (MPPD v 1.0): A model for human and rat airway particle dosimetry |
| Authors | Price, OT; Asgharian, B; Miller, FJ; Cassee, FR; de Winter-Sorkina, R |
| Publisher Text | National Institute for Public Health and the Environment (RIVM) |
| City | Bilthoven, Netherlands |
| Abstract | This model calculates the deposition and clearance of monodisperse and polydisperse aerosols in the respiratory tract of rats, human adults and children (deposition only) for particles ranging from ultrafine (0.01 microns) to coarse (20 microns) sizes. The models are based upon single-path and multiple-path methods for tracking air flow and calculating aerosol deposition in the lung. The single-path method calculates deposition in a typical path per airway generation, while the multiple-path method calculates particle deposition in all airways of the lung and provides lobar-specific and airway-specific information. Within each airway, deposition is calculated using theoretically derived efficiencies for deposition by diffusion, sedimentation and impaction within the airway or airway bifurcation. Filtration of aerosols by the head (nose and mouth) is determined using empirical efficiency functions. |
| Url | http://www.rivm.nl/bibliotheek/rapporten/650010030.html |
| Is Certified Translation | No |
| Dupe Override | No |
| Data Form | CD-ROM |
| Version | 1.0 |
| Comments | IN HERO Library |
| Is Public | Yes |
| Language Text | English |