Epidemiological study on Yusho babies born to mothers who had consumed oil contaminated by PCB
Yoshimura, T
| HERO ID | 202613 |
|---|---|
| In Press | No |
| Year | 1974 |
| Title | Epidemiological study on Yusho babies born to mothers who had consumed oil contaminated by PCB |
| Authors | Yoshimura, T |
| Journal | Fukuoka Igaku Zasshi |
| Volume | 65 |
| Issue | 1 |
| Page Numbers | 74-80 |
| Abstract | An epidemiological study was made of babies born between January 1967 and April 1972 to 108 Japanese families affected by Yusho. The purpose was to find babies born to mothers who had consumed rice oil contaminated with polychlorinated-biphenyls (1336363) (PCBs). The 27 babies born during this period were divided into three groups, depending on when the mother had consumed the contaminated oil. Group 1 consisted of breast fed babies whose mothers consumed the oil during the breast feeding period. Group 2 consisted of infants whose mothers consumed the oil during their pregnancies. Group 3 consisted of babies whose mothers ingested the oil prior to pregnancy. Of the 27 babies, 22 were surveyed, the other five having moved out of the area. Two of the seven babies fed with the mother's milk contaminated with PCB were definitely diagnosed as Yusho babies, being referred to as trans-milk Yusho babies. Two of the four babies classified in Group 2, their mothers having ingested contaminated oil during pregnancy, were definitely diagnosed as Yusho, being referred to as trans-placental Yusho babies. Of the 11 remaining babies, whose mothers consumed the contaminated oil prior to pregnancy, one was diagnosed as Yusho. Seven of the remaining ten showed symptoms of Yusho, dark gray skin or pigmentation of the gingiva at birth; however, they have not been diagnosed yet. These observations suggest that human milk secreted by mothers who had consumed the contaminated oil may contain PCB in sufficient concentration to affect the babies. As none of the mothers' milk was available, determination of PCB levels in the milk was not possible. It is also suggested that the mammary glands and placenta act as excretory passages. It is recommended that the infants be kept under continuous medical observation as a follow-up and that experiments be designed to find countermeasures for the toxins in polluted mother's milk. (Japanese: English translation available) |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | ID-701 |
| Is Public | Yes |
| Is Qa | No |