Hypoactivity in adolescent monkeys perinatally exposed to PCBs and hyperactive as juveniles

Bowman, RE; Heironimus, MP

HERO ID

201796

Reference Type

Journal Article

Year

1981

Language

English

HERO ID 201796
In Press No
Year 1981
Title Hypoactivity in adolescent monkeys perinatally exposed to PCBs and hyperactive as juveniles
Authors Bowman, RE; Heironimus, MP
Journal Neurobehavioral Toxicology and Teratology
Volume 3
Issue 1
Page Numbers 15-18
Abstract A group of three rhesus monkeys (M. mulatta) whose mothers had been fed 2.5 ppm PCBs (Aroclor 1248) in their diets through gestation and three months of nursing were tested for locomotor activity at 44 months of age. These animals had been hyperactive relative to controls at six and twelve months of age but were significantly hypoactive when compared to the same group of controls in the same apparatus in the 44-month test. Both groups showed within-session activity declines suggestive of reactivity which did not differ significantly between groups either within sessions or in their adaptation over the course of testing. This phenomenon represents a clear-cut delayed and possibly permanent effect of the early PCB exposure.
Wosid WOS:A1981LN38300004
Is Certified Translation No
Dupe Override No
Comments ID-793
Is Public Yes
Language Text English
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