Effect of creatinine on various experimentally induced inflammatory models
Madan, BR; Khanna, NK
| HERO ID | 1983173 |
|---|---|
| In Press | No |
| Year | 1979 |
| Title | Effect of creatinine on various experimentally induced inflammatory models |
| Authors | Madan, BR; Khanna, NK |
| Journal | Indian Journal of Physiology and Pharmacology |
| Volume | 23 |
| Issue | 1 |
| Page Numbers | 1-7 |
| Abstract | Creatinine, an aminoacid, has been studied for its anti-inflammatory activity. It is orally effective in suppressing the inflammatory responses produced by carrageenan, 5-hydroxytryptamine, nystatin and formaldehyde. It is observed that the antiinflammatory effect of creatinine is not owing to counter irritant action. It is suggested that it may partially be mediating its anti-inflammatory activity by interfering with the action or/and synthesis of prostaglandins. Like phenylbutazone it also possesses an analgesic action. |
| Pmid | 571414 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | Acute Disease; Administration, Oral; Analgesics/pharmacology; Animals; Anti-Inflammatory Agents; Carrageenan/pharmacology; Chronic Disease; Creatine/pharmacology; Creatinine/administration & dosage/ therapeutic use; Drug Evaluation; Edema/drug therapy; Formaldehyde/pharmacology; Inflammation/chemically induced/ drug therapy; Nystatin/pharmacology; Phenylbutazone/therapeutic use; Prostaglandin Antagonists; Serotonin/pharmacology |