CARCINOGENIC ACTION OF QUINOXALINE 1,4-DIOXIDE IN RATS
Tucker, MJ
| HERO ID | 1981917 |
|---|---|
| In Press | No |
| Year | 1975 |
| Title | CARCINOGENIC ACTION OF QUINOXALINE 1,4-DIOXIDE IN RATS |
| Authors | Tucker, MJ |
| Journal | Journal of the National Cancer Institute |
| Volume | 55 |
| Issue | 1 |
| Page Numbers | 137-146 |
| Abstract | Quinoxaline 1,4-dioxide was fed to 400 rats at levels of 10 mg or 1 mg/kg body weight for 18 months. It produced a high incidence of nasal and liver tumors only in the group fed 10 mg/kg. Of diverse histologies, the nasal tumors included anaplastic carcinomas, adenocarcinomas, squamous cell carcinomas, neuroepitheliomas, basal cell carcinomas, and a single fibrosarcoma. The nasal epithelium not involved in the neoplastic process showed dysplasia and hyperplasia. |
| Doi | 10.1093/jnci/55.1.137 |
| Pmid | 1159806 |
| Wosid | WOS:A1975AL92400022 |
| Url | <Go to ISI>://WOS:A1975AL92400022 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |