Immunological effects of environmental exposure to polychlorinated biphenyls and dioxins in Dutch school children

Weisglas-Kuperus, N; Vreugdenhil, HJI; Mulder, PGH

HERO ID

197026

Reference Type

Journal Article

Year

2004

Language

English

PMID

15093274

HERO ID 197026
In Press No
Year 2004
Title Immunological effects of environmental exposure to polychlorinated biphenyls and dioxins in Dutch school children
Authors Weisglas-Kuperus, N; Vreugdenhil, HJI; Mulder, PGH
Journal Toxicology Letters
Volume 149
Issue 1-3
Page Numbers 281-285
Abstract Perinatal exposure to PCBs and dioxins is associated with immune changes in healthy Dutch preschool children. To examine whether such effects persist into later childhood, we here report on the immunological effects of perinatal exposure to PCBs and dioxins in 167 Dutch children at school age. A higher postnatal PCB exposure was associated with a higher prevalence of recurrent middle ear infections and a higher prenatal PCB exposure with less shortness of breath with wheeze, as assessed by parent questionnaire. Our data indicate that, at environmental levels of these man made chemicals, subtle health effects may occur.
Doi 10.1016/j.toxlet.2003.12.039
Pmid 15093274
Wosid WOS:000221063400034
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Keyword PCBs; Dioxins; Immune changes; Pre-school children
Is Qa No