Surface characterization of completely degradable composite scaffolds
Charles-Harris, M; Navarro, M; Engel, E; Aparicio, C; Ginebra, MP; Planell, JA
HERO ID
1941927
Reference Type
Journal Article
Year
2005
Language
English
PMID
| HERO ID | 1941927 |
|---|---|
| In Press | No |
| Year | 2005 |
| Title | Surface characterization of completely degradable composite scaffolds |
| Authors | Charles-Harris, M; Navarro, M; Engel, E; Aparicio, C; Ginebra, MP; Planell, JA |
| Journal | Journal of Materials Science: Materials in Medicine |
| Volume | 16 |
| Issue | 12 |
| Page Numbers | 1125-1130 |
| Abstract | The goal of this study was to characterise the surface properties of completely degradable composite, polylactic acid and calcium phosphate glass, scaffolds. The composite scaffolds are made by solvent casting or phase-separation, using chloroform and dioxane as a solvent respectively. The surface properties were measured on composite films which were made using the same procedure as for the three-dimensional (3D) scaffolds without the pore-creating step. The surface morphology, roughness, wettability and protein adsorption capacity of the films was measured before and after sterilisation with ethylene oxide. The results reveal the influence of solvent type, glass weight content and sterilisation on the wettability, surface energy and protein adsorption capacity of the materials. The addition of glass particles increase the hydrophylicity, roughness and protein adsorption capacity of the surface. This effect, however, depends on the extent of the coating of the glass particles by the polymer film, which is much higher for dioxane films than for chloroform films. This information can be used to interpret and understand the biological behaviour of the 3D scaffolds made of this composite materials. |
| Doi | 10.1007/s10856-005-4717-4 |
| Pmid | 16362211 |
| Wosid | WOS:000234024000010 |
| Url | https://www.proquest.com/scholarly-journals/surface-characterization-completely-degradable/docview/756404154/se-2?accountid=171501 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Journal: ISSN: |
| Is Public | Yes |
| Language Text | English |
| Keyword | Engineering--Engineering Mechanics And Materials; Biocompatible Materials; Calcium Phosphates; Polymers; Proteins; poly(lactic acid); Lactic Acid; calcium phosphate; Adsorption; Composite materials; Microscopy, Electron, Scanning; Surface Properties; Proteins -- chemistry |