Analysis of the toxic mode of action of silver nanoparticles using stress-specific bioluminescent bacteria
Hwang, ET; Lee, JH; Chae, YJ; Kim, YS; Kim, BC; Sang, BI; Gu, MB
| HERO ID | 194065 |
|---|---|
| In Press | No |
| Year | 2008 |
| Title | Analysis of the toxic mode of action of silver nanoparticles using stress-specific bioluminescent bacteria |
| Authors | Hwang, ET; Lee, JH; Chae, YJ; Kim, YS; Kim, BC; Sang, BI; Gu, MB |
| Journal | Small |
| Volume | 4 |
| Issue | 6 |
| Page Numbers | 746-750 |
| Abstract | Every cell has a silver lining! The toxicity of Ag nanoparticles is investigated using a panel of recombinant bioluminescent bacteria. The presence of the nanoparticles leads to the production of a superoxide radical (see figure). Furthermore, the Ag nanoparticles damage the cellular membranes, causing a disruption in the ion efflux system. Thus, the cells cannot effectively extrude the Ag ions and, hence, Ag nanoparticles cause more damage than do Ag ions. |
| Doi | 10.1002/smll.200700954 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | N1-Analysis of the toxic mode of action of silver nanoparticles using stress-specific bioluminescent bacteriaID-11 |
| Is Public | Yes |
| Is Qa | No |