Development of an improved method to extract pesticide residues in foods using acetonitrile with magnesium sulfate and chloroform
Liu, G; Rong, L; Guo, B; Zhang, M; Li, S; Wu, Q; Chen, J; Chen, B; Yao, S
HERO ID
1940569
Reference Type
Journal Article
Year
2011
Language
English
PMID
| HERO ID | 1940569 |
|---|---|
| In Press | No |
| Year | 2011 |
| Title | Development of an improved method to extract pesticide residues in foods using acetonitrile with magnesium sulfate and chloroform |
| Authors | Liu, G; Rong, L; Guo, B; Zhang, M; Li, S; Wu, Q; Chen, J; Chen, B; Yao, S |
| Journal | Journal of Chromatography A |
| Volume | 1218 |
| Issue | 11 |
| Page Numbers | 1429-1436 |
| Abstract | A multiresidue method was developed based on extraction of 10 g sample with 10 mL acetonitrile and subsequent liquid-liquid partitioning formed by adding 4 g MgSO₄ plus 1 mL chloroform. During the partitioning process, the extraction recoveries of polar analytes were found to be essentially determined by the acetonitrile content in the aqueous phase. The use of MgSO₄ gave the least acetonitrile left in the aqueous phase (lower than 5%) and thus promoting complete partitioning of analytes into the organic phase. At the same time, removal of water from the acetonitrile phase was achieved by adding only a small amount of chloroform with no influence on the acetonitrile content in the aqueous phase, thus leading to decreasing the co-extraction of polar matrix components. The most complete mutual separation of acetonitrile and water was achieved by the joint use of MgSO₄ and chloroform and thus the optimal extraction recovery and analytical selectivity were obtained simultaneously. The new method, with higher recoveries of polar analytes, better analytical selectivity and simpler manipulation, is a claimed improvement to the original QuEChERS method. The proposed method was finally validated by the determination of 20 pesticides in a mixed food matrix by using liquid chromatography tandem mass spectrum (LC-MS/MS). Acceptable linearity, sensitivity, recovery, precision and selectivity results were obtained. |
| Doi | 10.1016/j.chroma.2011.01.041 |
| Pmid | 21296358 |
| Wosid | WOS:000288305200002 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | Multiresidue method; QuEChERS method; LC-MS/MS; Acetonitrile; MgSO4; Chloroform |