Determination method for xylidines in workplace air
Takeuchi, A; Yamamoto, S; Hendricks, W; Nishimura, Y; Imanaka, T; Kaifuku, Y; Sakui, N; Natsumeda, S; Ota, H; Yamada, S; Kurotani, I; Sumino, K; Kanno, S
| HERO ID | 1797722 |
|---|---|
| In Press | No |
| Year | 2011 |
| Title | Determination method for xylidines in workplace air |
| Authors | Takeuchi, A; Yamamoto, S; Hendricks, W; Nishimura, Y; Imanaka, T; Kaifuku, Y; Sakui, N; Natsumeda, S; Ota, H; Yamada, S; Kurotani, I; Sumino, K; Kanno, S |
| Journal | Journal of Occupational Health |
| Volume | 53 |
| Issue | 3 |
| Page Numbers | 230-233 |
| Abstract | <strong>OBJECTIVES: </strong>The purpose of this research was to develop a determination method for xylidines (XLDs) in workplace air for risk assessment.<br /><br /><strong>METHODS: </strong>The characteristics of the proposed method, such as recovery, detection limit, reproducibility, and storage stability of the samples were examined.<br /><br /><strong>RESULTS: </strong>An air sampler cassette containing two sulfuric acid-treated glass fiber filters was chosen as the sampler. The XLDs were extracted from the sampler filters, derivatized with heptafluorobutyric anhydride, and then analyzed by a gas chromatograph equipped with a mass spectrometer. The average recoveries of XLDs from the spiked sampler were 83-101% for personal exposure monitoring. The recovery after 5 days of storage in a refrigerator exceeded 90%. The overall limit of quantitation (LOQ) was 0.600 g/sample. The relative standard deviation, which represents the overall reproducibility defined as precision, was 0.8-10.3%.<br /><br /><strong>CONCLUSIONS: </strong>The proposed method enables 4-hour personal exposure monitoring of XLDs at concentrations equaling 0.001-2 times the threshold limit value-time-weighted average (TLV-TWA: 0.5 ppm) adopted by the American Conference of Governmental Industrial Hygienists, and is useful for estimating worker exposure to XLDs. |
| Doi | 10.1539/joh.10-0003-br |
| Pmid | 21422722 |
| Wosid | WOS:000291373900009 |
| Url | <Go to ISI>://WOS:000291373900009 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | Air Pollutants, Occupational; Aniline Compounds; 2,4-xylidine; 367R1L22C9; 2,5-xylidene; 95-78-3; 3,4-xylidine; R27I33AIDT; Index Medicus; Gas Chromatography-Mass Spectrometry; Threshold Limit Values; Environmental Monitoring -- methods; Occupational Exposure -- analysis; Aniline Compounds -- analysis; Air Pollutants, Occupational -- analysis |