Associations between fine and coarse particles and mortality in Mediterranean cities: Results from the MED-PARTICLES Project
Samoli, E; Stafoggia, M; Rodopoulou, S; Ostro, B; Declercq, C; Alessandrini, E; Díaz, J; Karanasiou, A; Kelessis, AG; Le Tertre, A; Pandolfi, P; Randi, G; Scarinzi, C; Zauli-Sajani, S; Katsouyanni, K; Forastiere, F
HERO ID
1790949
Reference Type
Journal Article
Year
2013
Language
English
PMID
| HERO ID | 1790949 |
|---|---|
| In Press | No |
| Year | 2013 |
| Title | Associations between fine and coarse particles and mortality in Mediterranean cities: Results from the MED-PARTICLES Project |
| Authors | Samoli, E; Stafoggia, M; Rodopoulou, S; Ostro, B; Declercq, C; Alessandrini, E; Díaz, J; Karanasiou, A; Kelessis, AG; Le Tertre, A; Pandolfi, P; Randi, G; Scarinzi, C; Zauli-Sajani, S; Katsouyanni, K; Forastiere, F |
| Journal | Environmental Health Perspectives |
| Volume | 121 |
| Issue | 8 |
| Page Numbers | 932-938 |
| Abstract | BACKGROUND: Few studies have investigated the independent health effects of different size fractions of particulate matter (PM), in multiple locations, especially in Europe. OBJECTIVES: We estimated the short-term effects of PM with aerodynamic diameter less than 10μm (PM10), less than 2.5μm (PM2.5), and between 2.5 and 10μm (PM2.5-10) on all-cause, cardiovascular and respiratory mortality in 10 European Mediterranean metropolitan areas within the MED-PARTICLES project. METHODSs: We analyzed data from each city using Poisson regression models, and combined city-specific estimates to derive overall effect estimates. We evaluated the sensitivity of our estimates to co-pollutant exposures and city-specific model choice, and investigated effect modification by age, sex, and season. We applied distributed lag and threshold models to investigate temporal patterns of associations. RESULTS: A 10-μg/m(3) increase in PM2.5 was associated with a 0.55% (95% CI: 0.27, 0.84%) increase in all-cause mortality (0-1 day cumulative lag), and a 1.91% increase (95%CI: 0.71, 3.12%) in respiratory mortality (0-5 day lag). In general, associations were stronger for cardiovascular and respiratory mortality than all-cause mortality, during warm versus cold months, and among those ≥ 75 versus <75 years of age. Associations with PM2.5-10 were positive but not statistically significant in most analyses, while associations with PM10 seemed to be driven by PM2.5 CONCLUSIONS: We found evidence of adverse effects of PM2.5 on mortality outcomes in the European Mediterranean region. Associations with PM2.5-10 were positive but smaller in magnitude. Associations were stronger for respiratory mortality when cumulative exposures were lagged over 0-5 days, and were modified by season and age. |
| Doi | 10.1289/ehp.1206124 |
| Pmid | 23687008 |
| Wosid | WOS:000323711700021 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | coarse particles; fine particles; Mediterranean; mortality; particulate matter; time series |