Sodium tungstate and vanadyl sulfate effects on blood pressure and vascular prostanoids production in fructose-overloaded rats
Peredo, HA; Zabalza, M; Mayer, MA; Carranza, A; Puyo, A
HERO ID
1753631
Reference Type
Journal Article
Year
2010
Language
English
PMID
| HERO ID | 1753631 |
|---|---|
| In Press | No |
| Year | 2010 |
| Title | Sodium tungstate and vanadyl sulfate effects on blood pressure and vascular prostanoids production in fructose-overloaded rats |
| Authors | Peredo, HA; Zabalza, M; Mayer, MA; Carranza, A; Puyo, A |
| Journal | Clinical and Experimental Hypertension |
| Volume | 32 |
| Issue | 7 |
| Page Numbers | 453-457 |
| Abstract | This study analyzes the effects of sodium tungstate and vanadyl sulphate in the fructose-overloaded rat, a model of metabolic syndrome. Fructose (9 weeks) increased blood pressure, triglycerydemia, glycemia, and reduced release of vasodilator prostaglandins (prostacyclin and prostaglandin E2 ) in the mesenteric vascular bed. Sodium tungstate prevented those alterations; meanwhile vanadyl sulfate only prevented the increase in glycemia. In conclusion, the present experiments showed that sodium tungstate is more effective than vanadyl sulfate for the treatment of experimental metabolic syndrome in rats. |
| Doi | 10.3109/10641961003686443 |
| Pmid | 21029009 |
| Wosid | WOS:000283593500008 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | tungstate; vanadyl; fructose; prostanoids; triglycerides |