Categorization framework to aid exposure assessment of nanomaterials in consumer products

Hansen, SF; Michelson, ES; Kamper, A; Borling, P; Stuer-Lauridsen, F; Baun, A

HERO ID

157560

Reference Type

Journal Article

Year

2008

Language

English

PMID

18454314

HERO ID 157560
In Press No
Year 2008
Title Categorization framework to aid exposure assessment of nanomaterials in consumer products
Authors Hansen, SF; Michelson, ES; Kamper, A; Borling, P; Stuer-Lauridsen, F; Baun, A
Journal Ecotoxicology
Volume 17
Issue 5
Page Numbers 438-447
Abstract Exposure assessment is crucial for risk assessment for nanomaterials. We propose a framework to aid exposure assessment in consumer products. We determined the location of the nanomaterials and the chemical identify of the 580 products listed in the inventory maintained by the Woodrow Wilson International Center for Scholars, of which 37% used nanoparticles suspended in liquids, whereas <1% contained "free airborne nanoparticles". C(60) is currently only used as suspended nanoparticles in liquids and nanosilver is used more as surface bound nanoparticles than as particles suspended in liquids. Based on the location of the nanostructure we were able to further group the products into categories of: (1) expected, (2) possible, and (3) no expected exposure. Most products fall into the category of expected exposure, but we were not able to complete a quantitative exposure assessment mainly due to the lack of information on the concentration of the nanomaterial in the products--a problem that regulators and industry will have to address if we are to have realistic exposure assessment in the future. To illustrate the workability of our procedure, we applied it to four product scenarios using the best estimates available and/or worst-case assumptions. Using the best estimates available and/or worst-case assumptions we estimated the consumer exposure to be 26, 15, and 44 microg kg(-1) bw year(-1) for a facial lotion, a fluid product, and a spray product containing nanoparticles, respectively. The application of sun lotion containing 2% nanoparticles result in an exposure of 56.7 mg kg(-1) bw d(-1) for a 2-year-old child, if the amounts applied correspond to the European Commission recommendations on use of sunscreen.
Doi 10.1007/s10646-008-0210-4
Pmid 18454314
Wosid WOS:000256314700010
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Keyword nanomaterials; categorization; exposure assessment; consumer products
Is Qa No