Toward a classification scheme for degrees of experimental evidence for the carcinogenicity of chemicals for animals
Griesemer, RA; Cueto, C, Jr
HERO ID
1502999
Reference Type
Book/Book Chapter
Year
1980
Language
English
PMID
| HERO ID | 1502999 |
|---|---|
| Year | 1980 |
| Title | Toward a classification scheme for degrees of experimental evidence for the carcinogenicity of chemicals for animals |
| Book Title | Molecular and cellular aspects of carcinogen screening tests |
| Authors | Griesemer, RA; Cueto, C, Jr |
| Editor | Montesano, R; Bartsch, H; Tomatis, L |
| Publisher Text | International Agency for Research on Cancer |
| City | Lyon, France |
| Volume | INT |
| Page Numbers | 259-281 |
| Abstract | A classification scheme is proposed for degrees of experimental evidence for the carcinogenicity of chemicals for animals. The classification stems from the suggestions of an IARC Working Group that the evaluation of bioassays include consideration of whether an increase in malignant tumours occurred and whether it occurred to an unusual degree or in multiple experiments. We extended the evaluative process to chemical experiments with no evidence of carcinogenicity and gave increased emphasis to results from more than one animal species. Although the proposed classification was developed for a group of NCI bioassays which were similar in design and conduct, it may provide a general framework for the evaluation of carcinogenesis bioassays and stimulate development and application of evaluative methods. |
| Pmid | 6893701 |
| Wosid | BCI:BCI198120027641 |
| Url | http://publications.iarc.fr/Book-And-Report-Series/Iarc-Scientific-Publications/Molecular-And-Cellular-Aspects-Of-Carcinogen-Screening-Tests-1980 |
| Is Certified Translation | No |
| Dupe Override | 1502999 |
| Conference Location | Hanover, Germany |
| Series | IARC Scientific Publications No. 27 |
| Isbn | 9789283211273 |
| Conference Name | Meeting organized by IARC and the Commission of the European Communities |
| Conference Date | June 4-9, 1979 |
| Comments | Journal: IARC ISSN: |
| Is Public | Yes |
| Language Text | English |
| Relationship(s) |
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