Proliferative and nonproliferative lesions of the rat and mouse respiratory tract

Renne, R; Brix, Amy; Harkema, J; Herbert, R; Kittel, B; Lewis, D; March, T; Nagano, K; Pino, M; Rittinghausen, S; Rosenbruch, M; Tellier, P; Wohrmann, T

HERO ID

1498639

Reference Type

Journal Article

Year

2009

Language

English

PMID

20032296

HERO ID 1498639
In Press No
Year 2009
Title Proliferative and nonproliferative lesions of the rat and mouse respiratory tract
Authors Renne, R; Brix, Amy; Harkema, J; Herbert, R; Kittel, B; Lewis, D; March, T; Nagano, K; Pino, M; Rittinghausen, S; Rosenbruch, M; Tellier, P; Wohrmann, T
Journal Toxicologic Pathology
Volume 37
Issue 7 Suppl.
Page Numbers 5S-73S
Abstract The INHAND Project (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) is a joint initiative of the Societies of Toxicologic Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP) and North America (STP) to develop an internationally-accepted nomenclature for proliferative and non-proliferative lesions in laboratory animals. The purpose of this publication is to provide a standardized nomenclature for classifying microscopic lesions observed in the respiratory tract of laboratory rats and mice, with color photomicrographs illustrating examples of some lesions. The standardized nomenclature presented in this document is also available electronically on the internet (http://www.goreni.org/). Sources of material included histopathology databases from government, academia, and industrial laboratories throughout the world. Content includes spontaneous developmental and aging lesions as well as lesions induced by exposure to test materials. A widely accepted and utilized international harmonization of nomenclature for respiratory tract lesions in laboratory animals will decrease confusion among regulatory and scientific research organizations in different countries and provide a common language to increase and enrich international exchanges of information among toxicologists and pathologists.
Doi 10.1177/0192623309353423
Pmid 20032296
Wosid WOS:000272556100001
Url http://<Go to ISI>://WOS:000272556100001
Is Certified Translation No
Dupe Override No
Comments Source: Web of Science WOS:000272556100001
Is Public Yes
Language Text English
Keyword respiratory system; lesions of the rat respiratory system; lesions of the mouse respiratory system
Is Peer Review Yes