Effects of vanadium on reproduction, gestation, parturition and lactation in rats upon oral administration

Domingo, JL; Paternain, JL; Llobet, JM; Corbella, J

HERO ID

1466104

Reference Type

Journal Article

Year

1986

Language

English

PMID

3747732

HERO ID 1466104
In Press No
Year 1986
Title Effects of vanadium on reproduction, gestation, parturition and lactation in rats upon oral administration
Authors Domingo, JL; Paternain, JL; Llobet, JM; Corbella, J
Journal Life Sciences
Volume 39
Issue 9
Page Numbers 819-824
Abstract Sodium metavanadate was tested for its effects on fetal development, reproduction, gestation and lactation in Sprague Dawley rats. Male rats were administered NaVO3 po at doses of 0, 5, 10 and 20 mg/kg/day for sixty days before mating with females which had received the same doses from 14 days previous to mating. These females received 0, 5, 10 and 20 mg NaVO3/kg/day during the periods of gestation and lactation. No significant adverse effects could be observed on: number of corpora lutea, implantations, live and dead fetuses, and resorptions. Significant decreases were observed in the development of the pups in all the vanadium -treated groups. All the doses used produced toxic effects in the offspring.
Doi 10.1016/0024-3205(86)90460-1
Pmid 3747732
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English