Development of a Practical One-Pot Synthesis of Indigo from Indole
Yamamoto, Y; Inoue, Y; Takaki, U; Suzuki, H
| HERO ID | 1463443 |
|---|---|
| In Press | No |
| Year | 2011 |
| Title | Development of a Practical One-Pot Synthesis of Indigo from Indole |
| Authors | Yamamoto, Y; Inoue, Y; Takaki, U; Suzuki, H |
| Journal | Bulletin of the Chemical Society of Japan |
| Volume | 84 |
| Issue | 1 |
| Page Numbers | 82-89 |
| Abstract | A novel and highly practical one-pot synthesis of indigo from indole via 3-position selective oxidation and dimerization of the indole framework was developed. Using 0.1 mol % of molybdenum complex and 2.2 equivalents of cumene hydroperoxide in tert-butyl alcohol, the reaction was complete in 7 h and pure indigo was obtained in 81% yield as a deep-blue solid just by filtration. The described one-step method renders the pure indigo readily available on a large scale using only inexpensive raw materials. |
| Doi | 10.1246/bcsj.20100134 |
| Wosid | WOS:000287835500010 |
| Url | http://joi.jlc.jst.go.jp/JST.JSTAGE/bcsj/20100134?from=CrossRef |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Source: Web of Science WOS:000287835500010 |
| Is Public | Yes |