Polyfluoroalkyl chemicals in house dust
Kato, K; Calafat, AM; Needham, LL
HERO ID
1424952
Reference Type
Journal Article
Year
2009
Language
English
PMID
| HERO ID | 1424952 |
|---|---|
| In Press | No |
| Year | 2009 |
| Title | Polyfluoroalkyl chemicals in house dust |
| Authors | Kato, K; Calafat, AM; Needham, LL |
| Journal | Environmental Research |
| Volume | 109 |
| Issue | 5 |
| Page Numbers | 518-523 |
| Abstract | We developed a high throughput analytical method using on-line solid phase extraction coupled with isotope dilution high-performance liquid chromatography-tandem mass spectrometry (on-line SPE-HPLC-MS/MS) to simultaneously determine the concentrations of 17 polyfluoroalkyl chemicals (PFCs) in house dust. The sample preparation includes dispersion of the dust samples in 0.1 M formic acid:MeOH (1:1), followed by agitation and filtration, addition of the isotope-labeled internal standard solution to the filtrate, and analysis by on-line SPE-HPLC-MS/MS. The limits of quantitation were <4.0 ng/g. The method accuracies ranged between 73.2% and 100.2% for the different analytes at two spike levels. We confirmed the validity of the method by analyzing 39 household dust samples collected in 2004. Of the 17 PFCs measured, 6 of them--perfluorobutane sulfonate (PFBuS), N-ethyl-perfluorooctane sulfonamide, 2-(N-ethyl-perfluorooctane sulfonamido) acetic acid (Et-PFOSA-AcOH), 2-(N-methyl-perfluorooctane sulfonamido) ethanol (Me-PFOSA-EtOH), perfluorohexane sulfonate (PFHxS), and perfluorooctane sulfonate (PFOS)--had detection frequencies >70%. We detected PFOS, PFBuS, and PFHxS at the highest median concentration, followed by Et-PFOSA-AcOH and Me-PFOSA-EtOH. |
| Doi | 10.1016/j.envres.2009.01.005 |
| Pmid | 19261270 |
| Wosid | WOS:000267277600002 |
| Url | https://search.proquest.com/docview/20642309?accountid=171501 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Source: Web of Science WOS:000267277600002 |
| Is Public | Yes |
| Language Text | English |
| Keyword | Dust; Polyfluoroalkyl chemicals; Exposure; PFCs |