[The action of phenylmercuriacetate and nitrate in combined application in rats: the thyroid gland, liver enzymes and morphologic findings in the brain and kidney]
Höring, H; Ellinger, C; Nagel, M; Páldy, A; Dési, I
| HERO ID | 1408272 |
|---|---|
| In Press | No |
| Year | 1986 |
| Title | [The action of phenylmercuriacetate and nitrate in combined application in rats: the thyroid gland, liver enzymes and morphologic findings in the brain and kidney] |
| Authors | Höring, H; Ellinger, C; Nagel, M; Páldy, A; Dési, I |
| Journal | Nahrung / Food |
| Volume | 30 |
| Issue | 7 |
| Page Numbers | 713-721 |
| Abstract | Rats were exposed to nitrate (NO3-) in drinking water, to phenylmercuryacetate (PMA) by gavage and to NO3- and PMA together during 4 different experiments. PMA impaired kidneys, NO3- thyroid gland, and NO3- and PMA together both organs. In the last case a synergistic effect on the thyroid gland was shown. The lowest effective concentration of NO3- was 40 mg/l. It resulted in histomorphological changes of the thyroid epithelial cells. That low effective dose of NO3- and possible synergistic effects should give a further impulse to take into consideration not only a low iodide intake but also goitrogenic environmental chemicals when evaluating the endemic goitre prevalence. |
| Pmid | 3773983 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | ger |