Pitfalls and solutions for the trace determination of phthalates in water samples

Tienpont, B; David, F; Dewulf, E; Sandra, P

HERO ID

1312190

Reference Type

Journal Article

Year

2005

Language

English

HERO ID 1312190
In Press No
Year 2005
Title Pitfalls and solutions for the trace determination of phthalates in water samples
Authors Tienpont, B; David, F; Dewulf, E; Sandra, P
Journal Chromatographia
Volume 61
Issue 7-8
Page Numbers 365-370
Abstract A method based on liquid-liquid extraction (LLE) and automated large volume injection (LVI)GC-MS analysis was developed for the trace determination of phthalate di-esters in water samples at sub-mu g L-1 (ppb) levels. Strategies applied to reduce contamination include (i) careful selection of tools, glassware and solvents, (ii) systematic blank checks of the chromatographic system, glassware and solvents and (iii) frequent verifications of blanks during sequences. Background levels could be reduced to those present in the extraction solvent. For phthalates not present in the extraction solvent the limits of quantitation (LOQ) are 6 ng L-1 for di-methyl phthalate (DMP), 3 ng L-1 for benzylbutyl phthalate (BzBP) and 45 ng L-1 for the isomeric phthalate mixtures di-isononyl phthalate (DiNP) and di-isodecyl phthalate (DOP). For the other phthalates, the LOQ was set at twice the blank (extraction solvent) level and are 20 ng L-1 for di-ethyl phthalate (DEP), 60 ng L-1 for di-isobutyl phthalate (DiBP), 80 ng L-1 for di-n-butyl phthalate (DBP) and 30 ng L-1 for bis-(2-ethylhexyl) phthalate (DEHP).
Doi 10.1365/s10337-005-0516-9
Wosid WOS:000228610300010
Url https://search.proquest.com/docview/2000001874?accountid=171501
Is Certified Translation No
Dupe Override No
Comments Source: Web of Science 000228610300010
Is Public Yes
Language Text English
Keyword gas chromatography; mass spectrometry; large volume injection; phthalate esters; water samples