Risk assessment for human consumption of perfluorinated compound-contaminated freshwater and marine fish from Hong Kong and Xiamen

Zhao, YG; Wan, HT; Law, AYS; Wei, X; Huang, YQ; Giesy, JP; Wong, MH; Wong, CKC

HERO ID

1274147

Reference Type

Journal Article

Year

2011

Language

English

PMID

21705041

HERO ID 1274147
In Press No
Year 2011
Title Risk assessment for human consumption of perfluorinated compound-contaminated freshwater and marine fish from Hong Kong and Xiamen
Authors Zhao, YG; Wan, HT; Law, AYS; Wei, X; Huang, YQ; Giesy, JP; Wong, MH; Wong, CKC
Journal Chemosphere
Volume 85
Issue 2
Page Numbers 277-283
Abstract Perfluorinated compounds (PFCs) are man-made fluoro-surfactants that are identified as global pollutants and can pose health risks to humans and wildlife. Two aspects of risk assessment were conducted in this study, including exposure and response. Exposure was estimated by using the concentrations of PFCs in fish and applying standard exposure factors. Among different PFCs, PFOS, PFOA, PFNA, PFDA, PFUdA and PFTrDA were detected. Total concentrations of PFC in fish ranged from 0.27-8.4 ng g(-1) to 0.37-8.7 ng g(-1) respectively in Hong Kong and Xiamen. The calculated hazard ratio (HR) of PFOS for all fish was less than 1.0. However, the HR for mandarin fish in Hong Kong and bighead carp, grass carp and tilapia in Xiamen, had HR values of approximately 0.5, indicating that frequent consumption of these 4 more contaminated fish species might pose an unacceptable risk to human health. Our data support the notion that the released/disposed chemical pollutants into water systems make fish a source of environmental toxicants to humans. The risks and potential effects of PFCs to health of coastal population in the Pearl River Delta are of concern.
Doi 10.1016/j.chemosphere.2011.06.002
Pmid 21705041
Wosid WOS:000297612700021
Url https://search.proquest.com/docview/1777170970?accountid=171501
Is Certified Translation No
Dupe Override No
Comments Source: Web of Science 000297612700021
Is Public Yes
Language Text English
Keyword PFCs; PFOS; LC-MS/MS; Hazard; Toxicity
Is Qa No