Reductive cleavage of azo compounds catalyzed by commercial zinc dust using ammonium formate or formic acid

Gowda, S; Abiraj, K; Gowda, DC

HERO ID

1164295

Reference Type

Journal Article

Year

2002

HERO ID 1164295
In Press No
Year 2002
Title Reductive cleavage of azo compounds catalyzed by commercial zinc dust using ammonium formate or formic acid
Authors Gowda, S; Abiraj, K; Gowda, DC
Journal Tetrahedron Letters
Volume 43
Issue 7
Page Numbers 1329-1331
Abstract Abstract: Azo compounds, both symmetric and unsymmetric, are cleaved to amine(s) by using commercial zinc dust and ammonium formate of formic acid in methanol, tetrahydrofuran or dioxane at room temperature. The reductive cleavage occurs without hydrogenolysis or hydrogenation of reducible moieties, such as -OH, -CH(3), -OCH(3), -COOH, - COCH(3), halogen, etc. The cleavage is very fast, clean, cost effective and high-yielding if compared with earlier methods, such as those using cyclohexene/5% Pd on asbestos, cyclohexane/10% Pd-C or hydrazine/10% Pd C or Raney nickel. (C) 2002 Elsevier Science Ltd. All rights reserved. ds: Chemistry cument Delivery No.: 526ED e field[29]: 1,4-Dioxane
Doi 10.1016/S0040-4039(01)02370-X
Wosid WOS:000174115800049
Url https://linkinghub.elsevier.com/retrieve/pii/S004040390102370X
Is Certified Translation No
Dupe Override No
Comments Source: Web of Science 000174115800049
Is Public Yes
Keyword ammonium formate; azo compounds; catalytic transfer hydrogenation; formic acid; reductive cleavage; zinc dust
Is Qa No