Determination of potential migrants in polycarbonate containers used for microwave ovens by high-performance liquid chromatography with ultraviolet and fluorescence detection
Nerin, C; Fernandez, C; Domeno, C; Salafranca, J
HERO ID
1157960
Reference Type
Journal Article
Year
2003
Language
English
PMID
| HERO ID | 1157960 |
|---|---|
| In Press | No |
| Year | 2003 |
| Title | Determination of potential migrants in polycarbonate containers used for microwave ovens by high-performance liquid chromatography with ultraviolet and fluorescence detection |
| Authors | Nerin, C; Fernandez, C; Domeno, C; Salafranca, J |
| Journal | Journal of Agricultural and Food Chemistry |
| Volume | 51 |
| Issue | 19 |
| Page Numbers | 5647-5653 |
| Abstract | The determination of several compounds present in a commercial polycarbonate container intended to be used in microwave ovens which could be considered as potential migrants has been carried out by reversed-phase high-performance liquid chromatography (HPLC) with both ultraviolet (UV) and fluorescence detectors. Total dissolution with dichloromethane and polymer reprecipitation with methanol have been used to evaluate 100% potential migration as the worst case. The extract consisted of a complex mixture containing monomers, oligomers, UV stabilizers, antioxidants, degradation products, and other additives. Phenol, Bisphenol A, 2,4-di-tert-butylphenol, Cyasorb UV5411, bis(2-ethylhexylphthalate), Irganox 1076, and Irgafos 168 were identified by both retention times and fluorescence-to-UV ratios. Additional confirmation was achieved by HPLC with diode array detection and gas chromatography-mass spectrometry. Recovery percentages were in the range of 73.8-94.4%, the lowest one being for the antioxidant Irgafos 168 due to its transformation into the phosphate form and 2,4-di-tert-butylphenol. The concentrations of the studied analytes present in the polycarbonate container ranged between 0.9 and 240 microg.g(-)(1). The total dissolution conditions that may affect the final concentration of analytes, mainly Bisphenol A, are discussed. |
| Doi | 10.1021/jf034330p |
| Pmid | 12952414 |
| Wosid | WOS:000185210100010 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Source: Web of Science 000185210100010 |
| Is Public | Yes |
| Language Text | English |
| Keyword | polycarbonate; additives; Bisphenol A; analysis; HPLC-UV-fluorescence; total dissolution |
| Is Qa | No |