Comparative assessment of antioxidant and cholinesterase inhibitory properties of the marigold extracts from Calendula arvensis L. and Calendula officinalis L

Ercetin, T; Senol, FS; Orhan, IE; Toker, G

HERO ID

1106469

Reference Type

Journal Article

Year

2012

Language

English

HERO ID 1106469
In Press No
Year 2012
Title Comparative assessment of antioxidant and cholinesterase inhibitory properties of the marigold extracts from Calendula arvensis L. and Calendula officinalis L
Authors Ercetin, T; Senol, FS; Orhan, IE; Toker, G
Journal Industrial Crops and Products
Volume 36
Issue 1
Page Numbers 203-208
Abstract Calendula sp. is an important medicinal and industrial plant with various bioactivities. In this study, we examined enzyme inhibitory effects of the n-hexane, dichloromethane, acetone, ethyl acetate, methanol, and water extracts of the leaf and flowers of Calendula arvensis L. and C. officinalis L. against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). The extracts were screened for their antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric ion-chelating capacity and ferric-reducing antioxidant power (FRAP) assays at 250, 500, and 1000 I14g mL super(-1. Total phenol and flavonoid quantification of the extracts was achieved using Folin-Ciocalteau and AlCl) sub(3) reagents, respectively. The ethyl acetate extract of C. arvensis flowers was the most active in AChE inhibition assay (31.24 +/- 1.29%), while the n-hexane extract of C. officinalis leaves exerted the highest ferric ion-chelating capacity (74.27 +/- 2.25%). Thin layer chromatographic analysis indicated presence of flavonoid and triterpene derivatives mainly in the extracts.
Doi 10.1016/j.indcrop.2011.09.007
Wosid WOS:000300921100030
Is Certified Translation No
Dupe Override No
Comments Source: Web of Science 000300921100030Scopus URL: https://www.scopus.com/inward/record.uri?eid=2-s2.0-80054111326&doi=10.1016%2fj.indcrop.2011.09.007&partnerID=40&md5=c5d860f3b74ebd0e8d91bbc847dd76c5
Is Public Yes
Language Text English
Keyword Calendula; Asteraceae; Marigold; Anticholinesterase; Antioxidant
Is Qa No