Total polyphenols, antioxidant and antiproliferative activities of different extracts in mungbean seeds and sprouts

Kim, DK; Jeong, SC; Gorinstein, S; Chon, SU

HERO ID

1038095

Reference Type

Journal Article

Year

2012

Language

English

PMID

22350499

HERO ID 1038095
In Press No
Year 2012
Title Total polyphenols, antioxidant and antiproliferative activities of different extracts in mungbean seeds and sprouts
Authors Kim, DK; Jeong, SC; Gorinstein, S; Chon, SU
Journal Plant Foods for Human Nutrition (Formerly Qualitas Plantarum)
Volume 67
Issue 1
Page Numbers 71-75
Abstract The aim of this investigation was to evaluate the biological, alcohol dehydrogenase (ADH) and antiproliferative activities of different extracts of mungbean seeds and sprouts. All extracts from the sprouts showed higher contents of total phenolics (TP), total flavonoids (TF), and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity than from seeds. The highest DPPH and tyrosinase inhibition activities were registered in ethyl acetate (EtOAc) extract. ADH activity of methanol (MeOH), n-hexane (n-hexane) and n-butanol (n-BuOH) extracts from sprouts was significantly higher (P < 0.05) than from seeds. However, the highest ADH activity was found in water extract of seeds. According to 3-(4, 5-dimethylthiazol -2-yl)-2, 5-diphenyltetrazolium bromide) (MTT) assay, extracts from sprouts were more effective against Calu-6 (human pulmonary carcinoma) and SNU-601 (human gastric carcinoma) cells than from seeds. EtOAc extract showed the highest antiproliferative activity in both sprouts and seeds, followed by n-hexane extraction. During sprouting of mungbean, all the studied components significantly increased. In conclusion, the extracts of sprouts are more effective than from seeds and could be a potential source of antioxidants linked with health benefits.
Doi 10.1007/s11130-011-0273-x
Pmid 22350499
Wosid WOS:000301789600011
Is Certified Translation No
Dupe Override No
Comments Source: Web of Science 000301789600011 Journal:PLANT FOODS FOR HUMAN NUTRITIONScopus URL: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84862804984&doi=10.1007%2fs11130-011-0273-x&partnerID=40&md5=030c4eb91a1c317c31c742332ca992e3
Is Public Yes
Language Text English
Keyword Mungbean seeds; Sprouts; Total phenolics; Total flavonoids; Antioxidant and antiproliferative activities
Is Qa No