Serum cholesterol levels in rats fed thirteen trace elements
Schroeder, HA
HERO ID
1032868
Reference Type
Journal Article
Year
1968
Language
English
PMID
| HERO ID | 1032868 |
|---|---|
| In Press | No |
| Year | 1968 |
| Title | Serum cholesterol levels in rats fed thirteen trace elements |
| Authors | Schroeder, HA |
| Journal | Journal of Nutrition |
| Volume | 94 |
| Issue | 4 |
| Page Numbers | 475-480 |
| Pmid | 5653261 |
| Url | http://jn.nutrition.org/content/94/4/475.long |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Toxnet Summary: The effects of trace elements on serum cholesterol were investigated. Rats were given drinking water containing 1 or 5 parts per million (ppm) of chromium (7440473) salt, 5ppm of soluble salts of zirconium (7440677), vanadium (7440622), niobium (7440031), nickel (7440020), cadmium (7440439), germanium (7440564), tin (7440315), lead (7439921), arsenic (7440382), or antimony (7440360), and 2ppm of selenium (7782492) or tellurium (13494809). Treatment was given from weaning until the rats were 11 to 30 months old. Blood samples were collected for determinations of serum cholesterol. After chromium exposure, serum cholesterol was reduced in males given 1ppm and females given 5ppm. Sex differences were evident in groups given vanadium, chromium, selenium, cadmium, germanium, tin, and control groups. For both sexes, the lowest serum cholesterol values were found in rats given niobium, chromium, and nickel. The highest values were found in those given tellurium. In males, increases also were seen in those given selenium, antimony, zirconium, and vanadium. Germanium decreased serum cholesterol in males. In females, high serum cholesterol values were found in the controls and in those given zirconium, cadmium, germanium, tin, lead, and arsenic. Low values occurred with vanadium, niobium, chromium, and nickel. The authors conclude that nickel, niobium, and chromium may possess anticholesterogenic properties, while tellurium may promote cholesterol formation. |
| Is Public | Yes |
| Language Text | English |
| Keyword | <?xml version="1.0" encoding="UTF-8"?><kw>DCN-117842</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Trace analysis</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Animal studies</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Chemical properties</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Metabolism</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Blood sampling</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Feeding study</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Dietary effects</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Laboratory testing</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Colorimetry</kw> |