Redirected to reference 61424
Screening of priority chemicals for reproductive hazards
HERO ID
61424
Reference Type
Technical Report
Subtype
TSCA Submission
Year
1983
Language
English
| HERO ID | 61424 |
|---|---|
| Material Type | TSCA Submission |
| Year | 1983 |
| Title | Screening of priority chemicals for reproductive hazards |
| Authoring Organization | Borriston Laboratories |
| Publisher Text | National Institute for Occupational Safety and Health |
| Abstract | The objective of this work was to determine the effect of nine chemicals on selected reproductive parameters in pregnant white mice. The nine chemicals were diethylene glycol diethyl ether, ethylenethiourea, sodium selenite, ethylene glycol dimethyl ether, diethylene glycol dimethyl ether, triethylene glycol dimethyl ether, p-nitrophenol, dimethyl phthalate, and naphthalene. The study was divided into two parts: (1) Determination of a Maximum Tolerated Dose (MTD) based on adult mortality and weight loss, and (2) A Reproductive Study in which the MTD dose was administered to pregnant SPF CD-1 mice. Both the MTD and reproductive portions of the investigation were completed in blocks of three chemicals each or a total of three blocks for the nine compounds. |
| Report Number | FYIOTS04830240IN |
| Ntis Number | OTS-0000240-0 |
| Url | https://ntrl.ntis.gov/NTRL/dashboard/searchResults.xhtml?searchQuery=PB83257600 |
| Is Certified Translation | No |
| Dupe Override | No |
| Number Of Pages | 116 |
| Is Public | Yes |
| Language Text | English |
| Relationship(s) |