OPPT_Cyclic Aliphatic Bromine Cluster (HBCD)_F. Human Health

Project ID

2563

Category

OPPT REs

Added on

March 8, 2017, 8:17 a.m.

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1431 items found. Displaying 25 items on page 1 of 58.

Journal Article

Applicability of the i/o-characters to a quantitative description of bioconcentration of organic chemicals in fish

Saito S, Tanoue, A, and Matsuo, M 1992

Abstract  The bioconcentrations factors (BCF's) of various types of organic chemicals in several fish species reported by Veith and Kosian were utilized to verify the applicability of SIGMAi and SIGMAo to describe their bioconcentration potentials quantitatively. A good linear correlations between logBCF and SIGMAi and SIGMAo was established over the 107 chemicals by a multiple regression: logBCF = -0.00458 | (0.00089) s = 0.735). The results suggest that SIGMAi and SIGMAo can be a good predictor of bioconcentration of organic chemicals in fish and broaden its applicability in this particular field.

Technical Report

A 90-day oral (gavage) toxicity study of HBCD in rats

American Chemistry Council 2002

Abstract  Final report of a 90-day oral gavage toxicity study in rats (converted from 8EHQ-0102-15040A) / A 90-Day Oral (Gavage) Toxicity Study of HBCD in Rats

Technical Report

Product information sheet, MSDS, and Toxicity Data Summaries: acute oral rats, acute dermal rabbits, primary skin irritation rabbits, eye irritation rabbits, acute inhalation rats, Ames test, acute fish toxicity test, pilot cataractogenic study in chicks, cataractogenic study in chicks, biodegradation, hydrolysis, partition coefficient, solubility

Great Lakes Chemical Corporation - Research & Development 1988

Abstract  Product information sheet, MSDS, and Toxicity Data Summaries: acute oral rats, acute dermal rabbits, primary skin irritation rabbits, eye irritation rabbits, acute inhalation rats, Ames test, acute fish toxicity test, pilot cataractogenic study in chicks, cataractogenic study in chicks, biodegradation, hydrolysis, partition coefficient, solubility,

Technical Report

Notice of initiation of 28-day repeated dose oral toxicity study of HBCD in rats

Chemical Manufacturers Association 1996

Abstract  Notice of initiation of 28-day repeated dose oral toxicity study of HBCD in rats

Technical Report

Notice of initiation of 7 studies on HBCD: acute fish test, acute daphnid test, algal toxicity test, analytical method verification for the determination of HBCD in well water, determination of water solubility, determination of n-octanol/water partition coefficient, evaluation of hydrolysis as a function of pH

Chemical Manufacturers Association 1996

Abstract  Notice of initiation of 7 studies on HBCD: acute fish test, acute daphnid test, algal toxicity test, analytical method verification for the determination of HBCD in well water, determination of water solubility, determination of n-octanol/water partition coefficient, evaluation of hydrolysis as a function of pH

Technical Report

Notice of initiation of a flow-through life-cycle toxicity test with the Cladoceran (Daphnia magna)

Chemical Manufacturers Association Brominated Flame Retardant Industry Panel 1998

Abstract  Notice of initiation of a flow-through life-cycle toxicity test with the Cladoceran (Daphnia magna)

Technical Report

Notice of initiation of a maximization test in guinea pigs and chromosomal aberrations in human peripheral blood

Chemical Manufacturers Association 1996

Abstract  Notice of initiation of a maximization test in guinea pigs and chromosomal aberrations in human peripheral blood

PubMed
DOI WoS
Journal Article

Role of thyroid hormones in human and laboratory animal reproductive health

Choksi NY et al. 2003

Abstract  The highly conserved nature of the thyroid gland and the thyroid system among mammalian species suggests it is critical to species survival. Studies show the thyroid system plays a critical role in the development of several organ systems, including the reproductive tract. Despite its highly conserved nature, the thyroid system can have widely different effects on reproduction and reproductive tract development in different species. The present review focuses on assessing the role of thyroid hormones in human reproduction and reproductive tract development and comparing it to the role of thyroid hormones in laboratory animal reproduction and reproductive tract development. The review also assesses the effects of thyroid dysfunction on reproductive tract development and function in humans and laboratory animals. Consideration of such information is important in designing, conducting, and interpreting studies to assess the potential effects of thyroid toxicants on reproduction and development.

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